Estimation of WBRT-Free Survival for Patients with 5 or More Brain Metastases Treated with Stereotactic Radiosurgery
Prognostic Features
Select Karnofsky Performance Status (KPS) (required)
Select Systemic Disease Status (required)
Select Increase in CNS-Activity Score of Systemic Therapy at Time of SRS† (required)
Select Histology (required)
Abbreviations and Legend
GI = Gastrointestinal
KPS = Karnofsky Performance Status
NED = No Evidence of Disease
NSCLC = Non-Small Cell Lung Cancer
RCC = Renal Cell Carcinoma
WBRT = Whole Brain Radiation Therapy
WBRT-Free Survival is an estimate of the probability of being alive at the indicated time without having needed salvage WBRT.
†Increase in CNS-Activity Score of Systemic Therapy was determined according NCCN guideline definitions. Please see the associated manuscript for details.
Disclaimer
These estimates are derived from nomograms developed and validated by researchers using patient data from UT MD Anderson Cancer Center. For more information about the details of the model, please refer to the published manuscript.
The estimate is based on data from a single institution and should not be considered professional medical advice. Always consult a healthcare provider for medical decisions.
Resources
- Beckham TH, Dudzinski SO, Rooney MK, Faraj CA, Pasli M, Perni S, Tom M, Ghia A, Yeboa DN, McAleer MF, Swanson T, McGovern S, Wang C, Chung C, De B, Jiang W, Kim BYS, Ferguson SD, Tawbi HA, Glitza I, Le X, Kaya D, Dumbrava EE, Briere T, Mackin D, Li J. Incorporating an NCCN-Based Systemic Therapy CNS Activity Score Into SRS Decision-Making for Patients With 5 or More Brain Metastases. J Natl Compr Canc Netw. 2026 Feb;24(2):34-40. doi: 10.6004/jnccn.2025.7103. PMID: 41671425.